Ramesh Dasari
Dr. Ramesh Dasari joined the Ursinus College faculty in 2024. He earned his PhD in Biology from Andhra University in India and completed postdoctoral training at the esteemed University of Pennsylvania and the University of Illinois Chicago.
The Dasari lab studies the molecular and genomic characteristics of prognostic factors in glioblastoma and ovarian cancers. Dr. Dasari is deeply invested in exploring and evaluating novel chemotherapeutic drugs to treat these challenging diseases. The lab investigates these conditions at the molecular and cellular levels using mouse models and clinical samples with meticulous attention to detail.
Department
Teaching
- Human Physiology
- Genetics
- Cell Biology
- Molecular Biology of Cancer
Research Interests
Cancer Biology and Drug Discovery
Research Interests:
- Studying the molecular and genomic characterization of prognostic factors in glioblastoma and ovarian cancer.
- Target-based chemotherapeutic development against glioblastoma and ovarian cancer.
Recent Work
Shivakumar M, Miller JE, Dasari VR, Zhang Y, Lee MTM, Carey DJ, Gogoi R, Kim D; DiscovEHR collaboration. Genetic Analysis of Functional Rare Germline Variants across Nine Cancer Types from an Electronic Health Record Linked Biobank. Cancer Epidemiol Biomarkers Prev. 2021 Sep;30(9):1681-1688.
Malla RR, Deepak K, Merchant N, Dasari VR. Breast Tumor Microenvironment: Emerging target of therapeutic phytochemicals. Phytomedicine. 2020 Apr 16;70:153227
Dasari VR, Carey DJ, Gogoi R. Synergistic enhancement of efficacy of platinum drugs with verteporfin in ovarian cancer cells. BMC Cancer. 2020 Apr 3;20(1):273.
Shivakumar M, Miller JE, Dasari VR, Gogoi R, Kim D. Exome-Wide Rare Variant Analysis from the DiscovEHR Study Identifies Novel Candidate Predisposition Genes for Endometrial Cancer. Front Oncol. 2019 Jul 5;9:574. eCollection 2019.
Miller JE, Metpally RP, Person TN, Krishnamurthy S, Dasari VR, Shivakumar M, Lavage DR, Cook AM, Carey DJ, Ritchie MD, Kim D, Gogoi R; DiscovEHR collaboration. Systematic characterization of germline variants from the DiscovEHR study endometrial carcinoma population. BMC Med Genomics. 2019 May 3;12(1):59.
Bang LG, Dasari VR, Kim D, Gogoi RP. Differential gene expression induced by Verteporfin in endometrial cancer cells. Sci Rep. 2019 Mar 7;9(1):3839.
